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SAM:在临床试验中动态借用历史数据的信息之前,自适应混合物

Peng Yang1,2, Yuansong Zhao3, Lei Nie4

  • 1Department of Statistics, Rice University, Houston, Texas, USA.

Biometrics
|September 18, 2023
PubMed
概括

根据数据证据,自适应混合物 (SAM) 先验者可以动态调整信息和非信息先验组件之间的平衡. 这种方法有效地管理了先前数据冲突,改善了研究中的统计建模.

关键词:
适应性设计是适应性的设计.动态信息借款 动态信息借款历史数据 历史数据混合物分布混合物分布的方法罕见的疾病 罕见的疾病现实世界的数据数据.

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