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在印度奈,从零售原奶样本中分离出的黄金葡萄球菌的流行率和特征

Shankaregowdanakopalu Jagadeesh Deepak¹, Porteen Kannan¹, Wilfred Ruban Savariraj²

¹Department of Veterinary Public Health and Epidemiology, Madras Veterinary College, TANUVAS, Chennai, Tamil Nadu, India.

Foodborne pathogens and disease

|September 18, 2023

概括

这项研究在印度奈的34%牛奶样本中发现金黄色葡萄球菌,显示出高遗传多样性和有关抗菌素耐药性 (AMR) 模式,包括多药耐药菌株.

科学领域:

食品微生物学食品微生物学
抗微生物耐药性抗微生物耐药性
公共卫生公共卫生

背景情况:

牛奶是各种微生物的营养丰富媒介.
黄金葡萄球菌 (Staphylococcus aureus) 是食用动物中一种重要的食源性病原体,由于其感染和抗菌素耐药性 (AMR),引起了全球公共卫生方面的担忧.

研究的目的:

从印度奈的牛奶样本中分离和描述金黄色葡萄球菌.
分析S. aureus分离物中确定的抗微生物耐药性 (AMR) 模式.

主要方法:

分析了来自奶牛场,当地供应商和零售商的259份原牛奶样本.
脉冲场凝电泳 (PFGE) 用于S. aureus分离物的遗传特征.
根据CLSI-M100性能标准对抗药物耐药性的表型评估.

主要成果:

34% (89/259) 的牛奶样本呈阳性S. aureus.
隔离物表现出高度的遗传多样性,在不同来源和位置之间没有相似之处.
所有分离物体对安培素有抗性,但对安培素/苏尔巴克坦,mupirocin和tylosin有敏感性.
28个分离物是多重耐药 (MDR),对2-3种抗菌类药物表现出耐药性.
关于乳制品S. aureus中可诱导的克林达米辛耐药性和mupirocin敏感性的第一份报告.

结论:

牛奶中黄金葡萄球菌的出现与基因多样性和奈地区的AMR模式的变化有关.
已确定的抗菌素耐药性概况,包括潜在的甲素耐药性黄金色杆菌 (MRSA),构成重大食品安全风险和经济影响.

关键词:

抗微生物耐药性抗微生物耐药性动物来源的动物食品.遗传多样性遗传多样性脉冲场凝电泳是一种脉冲场凝电泳.

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