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Updated: Jul 16, 2025

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
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BRWD3促进KDM5的降解,以保持H3K4甲基化水平

Dongsheng Han1, Samantha H Schaffner1, Jonathan P Davies1

  • 1Department of Biological Sciences, Vanderbilt University, Nashville, TN 37212.

Proceedings of the National Academy of Sciences of the United States of America
|September 18, 2023
PubMed
概括

代和WD重复含有蛋白3 (BRWD3) 通过控制KDM5的降解来调节基因组甲基化,该酶可消除H3K4甲基化标记. 这一发现揭示了维护染色体结构和基因表达平衡的新机制.

关键词:
这种植物是Drosophila.在这种情况下,染色染色素表观遗传学是指表观遗传学.甲基化处理 甲基化处理在任何地方都是无处不在的.

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