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Updated: Jul 16, 2025

Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist
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Published on: April 25, 2018

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光感应T细胞参与者触发,调整和塑造初级T细胞的激活

Morgane Jaeger1, Amandine Anastasio1, Léa Chamy1

  • 1Aix Marseille Université, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Centre d'Immunologie de Marseille Luminy, Turing Center for Living Systems, 13 288 Marseille, France.

Proceedings of the National Academy of Sciences of the United States of America
|September 18, 2023
PubMed
概括

研究人员开发了一种新的光遗传工具来研究T细胞受体 (TCR) 刺激动态. 该系统揭示了间歇性TCR信号如何差异激活T细胞类型和控制细胞因子释放,影响癌症免疫治疗.

关键词:
在T细胞激活过程中,在TCR中,可以使用TCR.双特异性T细胞参与者免疫学 免疫学 免疫学光学遗传学和光学遗传学.

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