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Updated: Jul 16, 2025

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
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引起ALS的基因会影响MHCII类抗原呈现途径

Binkai Chi1, Muhammet M Öztürk1, Christina L Paraggio1

  • 1Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.

Proceedings of the National Academy of Sciences of the United States of America
|September 18, 2023
PubMed
概括

与ALS相关的蛋白质的突变破坏了主要基因相容性复合体II (MHC II) 途径. 这种免疫系统衰竭可能会损害运动神经元的保护,从而导致ALS的进展.

关键词:
这就是ALS.C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C9ORF72C这就是FUS FUS.在MHC II中,MHC II是最重要的.

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