迷你粉碎或双吻粉碎后心血管结果复杂分叉病变的支架技术:EVOLUTE-CRUSH注册表
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Published on: March 28, 2025
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Ahmet Güner1, Fatih Uzun1, Gökhan Demirci1
1Department of Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
The American journal of cardiology
|September 18, 2023
概括
迷你粉碎 (MC) 和双吻粉碎 (DKC) 支架技术在复杂的冠状动脉分支病变中显示出类似的中期临床结果. 这两种方法都实现了高的成功率和低的并发症,提供了可比的目标病变失败率.
科学领域:
- 干预心脏病学 干预心脏病学
- 心血管研究研究心血管研究
- 医疗器械技术 医疗器械技术
背景情况:
- 复杂的冠状动脉分支病变在穿皮冠状动脉干预中带来了重大挑战.
- 现有的文献缺乏对这些复杂病变的双吻压缩 (DKC) 和迷你压缩 (MC) 支架技术之间的临床结果的直接比较.
- 中期随访数据对于评估不同分支支架支架策略的长期有效性和安全性至关重要.
研究的目的:
- 在患有复杂冠状动脉分支病变的患者中,比较DKC与MC支架技术的临床结果.
- 评估中期疗效和安全终点,包括目标病变衰竭 (TLF).
- 为干预性心脏病专家提供基于证据的见解,管理复杂的分叉病变.
主要方法:
- 对269名连续接受皮肤冠状动脉干预的复杂分叉病变患者进行了回顾性研究.
- 患者接受了MC技术 (132名患者) 或DKC技术 (137名患者) 的治疗.
- 主要终点是目标病变衰竭 (TLF),定义为心脏死亡,目标血管心肌梗塞或临床驱动的目标病变再血管化.
主要成果:
- 在DKC和MC组之间,SYNTAX得分相似 (p=0.631).
- DKC 组需要显著更多的气球,导线,并且有更长的光镜和手术时间 (p<0.001).
- 复合TLF率在MC (14%) 和DKC (12%) 组之间相似 (p=0.453),心脏死亡,MI,TLR和支架血栓形成的比较率相似.
结论:
- 两种MC和DKC支架技术在复杂的冠状动脉分支病变中都显示出高的血管学成功率和低的并发症率.
- 这两种技术的中期临床结果,特别是向病变失败,是相似的.
- 这些发现表明,无论哪种技术都可以安全地使用,尽管MC可能与更少的程序资源和更短的时间有关.
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