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Updated: Jul 16, 2025

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

Published on: March 10, 2018

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甲基氧化C-3和C-9 (S) -12-布罗莫斯托福利丁类似物,具有D1R抗剂活性

Hari K Namballa1, Ann M Decker2, Michael Dorogan1

  • 1Department of Chemistry, Hunter College, City University of New York, 695 Park Avenue, NY 10065, United States.

Bioorganic chemistry
|September 18, 2023
PubMed
概括

新型四原柏林 (THPB) 类似物被合成并测试多巴胺D1受体 (D1R) 活性. 修改C-3位置显示出有前途的D1R抗体潜力,具有良好的血脑屏障透.

关键词:
D1R 是一个D1R.多巴胺是一种多巴胺.斯蒂福利迪因 (Stepholidine) 是一种药物.在THPBB中,我们可以使用THPB.这是一种四水原柏胺 (Tetrahydroprotoberberine).这是一种β-阿雷斯因.

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