使用热成像对颗粒温度的可视化,以更好地理解连续双螺旋融颗粒处理中的颗粒化机制

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S Van de Steene1, J Van Renterghem1, V Vanhoorne2

  • 1Laboratory of Pharmaceutical Process Analytical Technology, Faculty of Pharmaceutical Sciences Ghent University, Ghent, Belgium.

International journal of pharmaceutics
|September 18, 2023
PubMed
概括

双螺丝融化颗粒的螺丝配置显著影响颗粒温度和形成. 优化的扎区,特别是反向的小转折角,提高了颗粒质量和温度控制.

关键词:
连续制造 连续制造制造颗粒化机制 颗粒化机制热化颗粒化方法双螺丝颗粒剂的颗粒化方法双螺丝化颗粒化融技术

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