辅助生殖技术和心血管结果在父母和后代
Shu Qin Wei1, Gilles Paradis2, Aimina Ayoub3
1Department of Obstetrics and Gynaecology, University of Montréal, Montréal, Québec, Canada; Institut national de santé publique du Québec, Montréal, Québec, Canada.
The Canadian journal of cardiology
|September 18, 2023
概括
辅助生殖技术 (ART) 稍微增加了母亲和后代的心血管风险,包括先天性心脏缺陷和高血压. 然而,ART对家庭的心血管系统没有重大长期影响.
科学领域:
- 心血管健康 心血管健康
- 生殖医学 生殖医学
- 公共卫生 公共卫生
背景情况:
- 辅助生殖技术 (ART) 对心血管的影响需要进一步研究.
- 了解ART对家庭心血管健康的影响至关重要.
研究的目的:
- 评估ART与家族心血管疾病之间的关联.
- 评估 ART 怀孕后母亲,父亲和后代的风险.
主要方法:
- 对超过100万例怀孕 (2008-2019) 的回顾性纵向队列研究.
- 比较ART怀孕与自然怀孕的怀孕.
- 分析了严重的母亲心血管疾病,后代先天性心脏缺陷和长期心血管住院病例.
主要成果:
- 与2.04倍严重的孕产妇心血管疾病风险相关的ART.
- ART与子女患先天性心脏缺陷的1.38倍风险有关.
- 增加了父亲和后代的心血管住院的风险,主要是由于高血压.
结论:
- 在家庭中,ART与心血管风险的小幅增加有关.
- 对父母和后代来说,ART可能不会对心血管系统产生重大不良影响.
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