病例报告:免疫功能低下患者中Kocuria palustris Bacteremia的病例系列
Gerlin Varghese1, Ashima Jamwal1, Deepika Sarawat1
1Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
The American journal of tropical medicine and hygiene
|September 18, 2023
概括
Kocuria palustris是一种机会性病原体,在接受化疗或血液透析的三名免疫受损患者中引起了细菌病. 早期发现和治疗对于降低这些脆弱个体的死亡率至关重要.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 临床细菌学 临床细菌学
背景情况:
- 科库里亚物种通常是共生性皮肤细菌,通常被认为是非致病性.
- 最近的文献表明,Kocuria物种在人类感染中起到了新兴的作用.
- Kocuria palustris被认为是一种机会性病原体,有可能在免疫受损的宿主中引起严重疾病.
研究的目的:
- 突出 Kocuria palustris 作为免疫功能低下患者细菌病的原因的新兴威胁.
- 强调准确及时识别Kocuria palustris对于有效治疗的重要性.
- 在特定患者群体中报告Kocuria palustris bacteremia的临床病例.
主要方法:
- 一系列病例报告了免疫功能低下患者三例细菌病例.
- 血液培养物被分析为细菌分离物.
- 使用飞行质谱的矩阵辅助激光溶解离子化时间测量 (MALDI-ToF MS) 进行了Kocuria palustris的鉴定.
主要成果:
- 三名免疫功能低下的患者 (胆囊癌,血液透析中的慢性脏病,急性髓性白血病) 患上了Kocuria palustris bacteremia.
- 所有患者在各自的治疗过程中出现了发烧和中性衰竭.
- 血液培养产生了Kocuria palustris的纯分离物,由MALDI-ToFMS证实.
结论:
- Kocuria palustris可以导致严重的感染,如细菌病,在免疫受损的个体.
- 及时诊断和适当的抗生素治疗对于管理Kocuria palustris感染和改善患者的治疗结果至关重要.
- 这一案例系列强调了需要提高对Kocuria palustris作为机会性病原体的临床意识的必要性.
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