双盲随机对照试验的协议,调查在手腕道释放中使用辅助碳酸盐:单中心研究
Mikael Hytönen1, Yrjänä Nietosvaara2,3,4, Aleksi Reito5
1School of Medicine, University of Eastern Finland, Kuopio, Finland mikael.hytonen@outlook.com.
BMJ open
|September 18, 2023
概括
缓冲局部麻醉剂可以减少手腕道释放 (CTR) 手术期间的疼痛. 这项随机试验比较了缓冲与非缓冲的利多卡因和布皮瓦卡因在CTR患者的疼痛管理中.
科学领域:
- 手术手术手术手术手术
- 疼痛管理 疼痛管理
- 麻醉学 麻醉学
背景情况:
- 带道释放 (CTR) 是最常见的手术,通常在局部麻醉下进行.
- 在局部麻醉注射期间的疼痛是CTR期间患者的重要关注点.
- 长效局部麻醉剂和缓冲剂可以改善疼痛控制.
研究的目的:
- 为了比较缓冲和非缓冲的长效局部麻醉剂在CTR期间和之后缓解疼痛的有效性.
- 为了评估患者报告的疼痛,止痛药的使用,以及CTR后的功能结果.
主要方法:
- 这是一项随机对照试验,涉及116名手腕道综合征 (CTS) 患者.
- 患者将在CTR之前接受缓冲或非缓冲的利多卡因和布皮瓦卡因与上腺素.
- 使用视觉模拟量表 (VAS) 评估疼痛,其次要结果包括疼痛强度,止痛药消耗和功能状态.
主要成果:
- 主要结局:局部麻醉注射 (VAS) 期间的整体疼痛.
- 二次结局:疼痛强度,止痛药的使用,症状严重程度和手术后3个月的功能状态.
- 患者评级的结果将在手术后3个月评估.
结论:
- 这项研究将提供关于缓冲局部麻醉剂在减少CTR过程和术后疼痛方面的疗效的证据.
- 这些发现将为临床实践提供关于手术最佳局部麻醉准备的信息.
- 结果旨在通过改善手腕道释放期间和释放后的疼痛管理来提高患者的满意度.
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