非心脏手术后术后认知功能障碍的频率及其对功能结果的影响:系统审查的协议
Yetiani Roldan1, Shahzaib Khattak2, Saif Samari2
1Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
BMJ open
|September 18, 2023
概括
本系统性综述研究了老年手术患者的术后认知功能障碍 (POCD). 它评估POCD的频率,它与非心脏手术的联系,以及它对患者结果的影响.
科学领域:
- 老年医学 老年医学
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
背景情况:
- 年龄较大的外科候选人面临术后认知功能障碍 (POCD) 的风险增加.
- 现有的研究方法不同,因此很难确定POCD的真实发病率和影响.
- 对POCD的频率和后果的全面了解对于患者护理至关重要.
研究的目的:
- 系统地审查和评估对非心脏手术后POCD的研究.
- 为了确定POCD的频率 (RQ1).
- 评估非心脏手术是否会增加认知能力下降的风险 (RQ2).
- 评估POCD与患者重要结局之间的关联 (RQ3).
主要方法:
- 在MEDLINE,PsycINFO和EMBASE的系统文献搜索.
- 由两个独立审查员进行选和数据提取.
- 使用已有的工具进行质量评估 (QIPS,CLARITY).
- 在可行的情况下,对POCD频率 (RQ1) 和手术与认知衰退 (RQ2) 和结局 (RQ3) 的关联进行元分析.
主要成果:
- 该审查将综合在手术后的不同时间点对POCD发病率的发现.
- 它将量化非心脏手术和认知衰退之间的关联.
- 将分析POCD对功能状态和生活质量的影响.
结论:
- 这一综述将为老年手术患者的POCD提供一个综合的概述.
- 结果将为临床实践和未来的研究方向提供信息.
- 了解POCD的影响对于改善手术结果和患者福祉至关重要.
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