现实世界的治疗模式和白内障后黄斑的经济负担
Gina Ahmadyar1,2, Josh J Carlson3, Alan Kimura4
1AbbVie Inc, 2525 DuPont Drive, 92612, Irvine, CA, USA. gina.ahmadyar@abbvie.com.
BMC ophthalmology
|September 18, 2023
概括
白内障后黄斑 (PCME) 显著增加了医疗保健成本和资源使用,观察到不同的治疗模式. 标准化PCME干预措施可以改善结果,并减少患者和支付人的经济负担.
科学领域:
- 眼科医生 眼科 眼科
- 卫生经济学 卫生经济学
背景情况:
- 如果不治疗,白内障后黄斑 (PCME) 可以导致视力丧失,但缺乏标准化的治疗指南.
- 关于PCME的经济影响和现实世界治疗模式的数据有限.
研究的目的:
- 为了评估PCME的现实世界治疗模式.
- 评估与PCME相关的经济负担.
主要方法:
- 使用IBM MarketScan数据库对患有PCME和没有PCME的患者进行回顾性索赔分析.
- 倾向性得分匹配 (1:3) 对患者特征的控制.
- 分析治疗线路,眼科访问,OCT扫描和药物费用.
主要成果:
- 在PCME治疗中显著的临床变异性,包括局部类固醇,NSAID和注射剂.
- PCME患者的费用更高,平均6次额外的眼科检查,总费用增加了3,897美元.
- PCME患者填写了另外3份眼科处方,增加了371美元的费用.
结论:
- PCME治疗模式表现出很大的变化,特别是在注射疗法和组合治疗中.
- PCME导致医疗保健资源利用率显著提高,并为患者和纳税人带来经济负担.
- 对治疗标准化的需要和PCME预防策略的潜在价值.
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