在简单的相互抑制系统中,噪声诱导的可比性
Taichi Haruna1, Tomohiro Shirakawa2
1Department of Information and Sciences, School of Arts and Sciences, Tokyo Woman's Christian University, 2-6-1 Zempukuji, Suginami-ku, Tokyo 167-8585, Japan.
Physical review. E
|September 19, 2023
概括
这项研究揭示了噪音如何在相互抑制系统中诱导可比性. 从单模向双模概率密度的过渡被证明即使在单调的外部信号中也会发生.
科学领域:
- * 计算神经科学和理论生物学.
- *专注于动态系统和随机过程.
背景情况:
- *双稳定性,即两个稳定的状态的存在,在生物系统中至关重要.
- * 了解噪声诱导的转变是解释生物变异性的关键.
研究的目的:
- *在双变的相互抑制系统中建立噪声诱导的可比性的一个一般条件.
- * 调查这种过渡背后的机制,特别是它与单调的外部信号发生的机制.
主要方法:
- * 分析一种简单的双变异性相互抑制系统,反应缓慢而波动.
- * 计算平均第一次过渡时间以阐明过渡机制.
- * 对边际静止概率密度函数的检查.
主要成果:
- * 从单模向双模概率密度过渡的一般条件得到了推导.
- *即使对外部信号的响应是单调的,这种过渡也被证明会发生.
- * 平均第一通道时间分析揭示了观察到的双稳定性的基本机制.
结论:
- * 噪声可以在相互抑制系统中强有力的诱导双稳定性,无论信号单调性如何.
- * 确定过渡机制是一般的,适用于各种生物环境.
- * 进一步讨论了这种噪声诱导的双稳定性机制的通用性.
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