在人类瘤中对STAT3表达和遗传变化的泛癌分析

Junyin Tan1, Ronghao Feng1

  • 1Department of Oncology, Guigang People's Hospital of Guangxi/The Eighth Affiliated Hospital of Guangxi Medical University, Guigang, Guangxi, China.

PubMed
概括

信号传感器和转录3激活器 (STAT3) 的过度表达通过改变免疫微环境促进瘤生长,与低度质瘤的不良预后相关. 有针对性的STAT3抑制在联合癌症疗法方面显示出前景.