基于PEO-PPO-PEO的块共聚合物的盐诱导化行为:一种热响应的方法
Nitumani Tripathi1, Debes Ray2,3, Vinod K Aswal2
1Department of Chemistry, Sardar Vallabhbhai National Institute of Technology (SVNIT), Ichchhanath, Surat-395 007, Gujarat, India. ketankuperkar@gmail.com.
Soft matter
|September 19, 2023
概括
乙烯氧化物和氧化物块共聚合物通过盐或热在水中形成有组织的微粒. 这些Pluronics®自组件增强了疏水性染料的溶解性.
科学领域:
- 聚合物科学 聚合物科学
- 材料科学 材料科学 材料科学
- 物理化学 物理化学
背景情况:
- 基于乙烯氧化物 (EO) 和氧化物 (PO) 的块共聚物 (BCP),称为Pluronics®,在水溶液中表现出独特的自我组装.
- 由于其独特的聚乙烯氧化物 (PEO) 和聚烯氧化物 (PPO) 分段比率,Pluronics® L44和F77在水友性上有所不同.
研究的目的:
- 研究Pluronics® L44和F77在水溶液中的纳米自组装行为.
- 确定盐 (NaCl,Na2SO4) 和温度对BCP微粒化的影响.
- 评估形成的微粒的溶解能力,以获得疏水性染料.
主要方法:
- 使用了包括相位行为,热度计,张力计,散射和光谱分析在内的物理化学技术.
- 测量了单体和状结构的水力动力学大小 (Dh).
- 使用光谱方法评估色OT染料的溶解度.
主要成果:
- 在20-30°C和10%的w/v度下,Pluronics®存在于unimers (4-6nm) 或松散集群中.
- 较高的度,盐的存在或升高的温度促进了有组织的球形或圆形菌根的形成.
- 在状系统内观察到色OT水染料溶解的显著增强.
结论:
- 盐和高温诱导了Pluronics®的自我组装成明确的状结构.
- 形成的Pluronics®微粒显示出具有溶解疏水化合物的潜力.
- 了解这些自组装动态对于药物输送和纳米技术的应用至关重要.
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