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在移植中抗体中介排斥的文献计量和知识图分析
Jinhua Zhang1, Xiaowen Yu2, Zhenwei Xie1
1Department of kidney transplantation, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Renal failure
|September 19, 2023
概括
抗体介导排斥 (AMR) 是移植的一个主要挑战. 本文献分析揭示了移植结果和非侵入性策略,如无细胞DNA,是改善移植存活的关键未来研究领域.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 免疫学 免疫学 免疫学
- 移植科学 移植科学
背景情况:
- 抗体介导排斥 (AMR) 显著阻碍了长期移植的生存.
- 迫切需要新的AMR预防和治疗策略.
- 图书统计分析为科学领域的研究趋势和方向提供了洞察力.
研究的目的:
- 在移植中对抗体介导排斥 (AMR) 的研究进行文献分析.
- 从1999年到2022年,确定AMR研究的现状和新兴趋势.
主要方法:
- 从Web of Science核心收藏中对1999年至2022年间发表的2522篇文章进行了图书统计分析.
- 使用HistCite,CiteSpace,Bibliometrix和Gephi来分析出版趋势,主要贡献者,核心期刊和关键词.
- 审查年度出版物,贡献国家/地区,机构,作者和有影响力的参考文献.
主要成果:
- 与移植中AMR相关的年度出版物持续增加.
- 美国在文章数量和引文数量方面处于领先地位,其中包括70个国家和118个机构.
- 主要研究领域包括移植结果,存活率和临床研究,重点关注 dd-cfDNA 等非侵入性方法.
结论:
- 北美和欧洲地区是AMR研究的核心.
- 未来的研究热点包括AMR的预后.
- 非侵入性策略,特别是血和尿液的dd-cfDNA,显示出促进抗菌耐药性研究和管理的巨大潜力.
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