在骨关节炎患者中使用处方止痛药
Zhenzhen Huang1, Xinxin Chen2, Xihong Gan3
1Department of Pharmacy, The Third People's Hospital of Cangnan, Wenzhou, China.
Journal of orthopaedic surgery (Hong Kong)
|September 19, 2023
概括
在骨关节炎患者中,阿片类药物的使用仍然很高,而 gabapentinoid 的使用迅速增加. 长期使用阿片类药物是一个重大问题,强调需要改进疼痛管理策略和患者教育.
科学领域:
- 类风湿病学 类风湿病学
- 疼痛管理 疼痛管理
- 公共卫生 公共卫生
背景情况:
- 骨关节炎 (OA) 药物治疗通常涉及止痛药.
- 了解处方模式对于有效的OA疼痛管理至关重要.
- 由于潜在的长期风险,OA患者的阿片类药物使用需要仔细监测.
研究的目的:
- 分析美国OA患者处方止痛药使用的趋势和模式.
- 在OA人口中确定与阿片类药物使用相关的人口特征.
- 为在OA中管理阿片类药物使用的战略提供信息.
主要方法:
- 从国家健康和营养检查调查 (NHANES) 中分析了2214名OA患者 (2007-2018) 的数据.
- 在OA患者和非OA个体之间比较止痛药和抗抑郁药的使用情况.
- 对处方药的使用情况进行分类分析.
主要成果:
- NSAIDs,乙胺和 gabapentinoids 是OA的常见止痛药. 这是OA的常见止痛药.
- 阿片类药物使用普遍 (7.7%) 持续时间长,从2007年至2018年没有减少.
- gabapentinoid的使用显著增加 (5.0%至12.1%),常见的组合包括阿片类药物/乙氨基和 gabapentinoids/SSRI.
结论:
- gabapentinoid 的使用正在增加,而阿片类药物的使用仍然是OA 疼痛管理中持续存在的问题.
- 长期,过度使用阿片类药物对OA疼痛控制构成严重挑战.
- 加强医疗保健教育,非药物治疗方法和心理支持对于OA患者护理至关重要.
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