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炎症性肠病缓解期患者的腹痛:对促进因素的前性研究
L M Janssen1,2, A Rezazadeh Ardabili1,2, M J L Romberg-Camps3
1Department of Internal Medicine-, Division of Gastroenterology and Hepatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Alimentary pharmacology & therapeutics
|September 19, 2023
概括
腹部疼痛在患有炎症性肠病 (IBD) 的患者中很常见,即使在缓解期. 压力和疲劳等心理社会因素与这种疼痛有显著的关联,这表明需要采用整体治疗方法.
科学领域:
- 胃肠病学 胃肠病学
- 精神病体医学是一种精神病体医学.
- 临床研究 临床研究
背景情况:
- 腹部疼痛是炎症性肠病 (IBD) 患者在缓解期的常见症状.
- 这种持续的腹痛的根本原因尚未完全理解.
研究的目的:
- 研究临床,生活方式和心理社会因素与IBD缓解期患者腹痛的发生之间的关联.
- 在一个明确的IBD队列中确定导致慢性腹痛的关键因素.
主要方法:
- 一项涉及559名IBD患者的前性多中心研究于2020年1月至2021年7月进行.
- 在18个月内,通过myIBDcoach平台收集了有关疾病活动,生活方式和心理社会福祉的数据.
- 慢性腹痛缓解期 (IBDremissionPain+) 用经过验证的评分系统和便calprotectin水平来确定.
主要成果:
- 几乎一半 (46.2%) 的生化缓解患者经历了慢性腹痛.
- 疼痛患者更有可能是女性,年轻,BMI更高,疾病持续时间更短.
- 在腹痛和更高水平的压力,疲劳,抑郁和焦虑症状以及生活事件之间发现了显著的关联.
结论:
- 心理社会因素在IBD缓解期患者的腹痛体验中发挥着重要作用.
- 建议采用综合的,整体的治疗策略,同时解决身体和心理方面的问题,以改善患者的护理和幸福感.
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