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将离散时间的赖特-费舍尔模型扩展到生物库规模的数据集

Jeffrey P Spence1, Tony Zeng1, Hakhamanesh Mostafavi1

  • 1Department of Genetics, Stanford University, Stanford, CA 94305, USA.

Genetics
|September 19, 2023
PubMed
概括

一个新的可扩展算法接近于离散时间的赖特-费舍尔模型,使得数以百万计的人口遗传学分析成为可能. 这种方法提高了从大型遗传数据集中估计选择系数的准确性.

关键词:
赖特 费舍尔 在功能丧失 - 功能丧失选择的选择选择的选择.

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