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Spatial Separation of Molecular Conformers and Clusters
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在充电滴中封装会产生扭曲的宿主-客人综合体
Daniel L Stares1, Agnieszka Szumna2, Christoph A Schalley1
1Institut für Chemie und Biochemie, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Chemistry (Weinheim an der Bergstrasse, Germany)
|September 19, 2023
概括
树脂烯囊通过电喷离子化 (ESI) 方式将长客体结合在充电液滴中,克服了溶液的限制. 这些紧张的"弹载荷"复合体是由于气相中增强的非共价相互作用而形成的.
科学领域:
- 超分子化学 超分子化学
- 物理化学 物理化学
- 分析化学 分析化学
背景情况:
- 结合的复星烯囊是已知的宿主分子.
- α,ω-alkylbisDABCOnium (DnD) 的客体是有机分子.
- 溶液中的宿主-客人化学往往受到竞争相互作用的限制.
研究的目的:
- 为了研究DnD客人被Resorcinarene囊封装.
- 通过电喷离子化 (ESI) 在气相中探索宿主-客座复合体的形成.
- 为了确定这些复合物的结合模式和稳定性.
主要方法:
- 电子喷射电离 (ESI) 质谱法. 电子喷射电离 (ESI) 质谱法. 电子喷射电离 (ESI) 质谱法. 电子喷射电离 (ESI) 质谱法. 电子喷射电离 (ESI) 质谱法.
- 碰撞引起的解离 (CID) 和/ (H/D) 交换.
- 离子移动性质谱 (IM-MS) 和计算建模.
主要成果:
- 通过Resorcinarene囊对DnD客体进行封装,是在充电ESI滴中实现的,而不是溶液中.
- 即使是过长的客人也被封装起来,需要客人和主机的显著扭曲.
- 综合体采用了类似马的客体构造来优化-π相互作用.
结论:
- 在ESI滴中的气相封装绕过了诸如离子配对等溶液相限制.
- 紧张的"弹载"宿主-客体复合体在没有溶剂的情况下通过增强的非共价相互作用来稳定.
- 由ESI生成的带电滴提供了一个独特的环境来研究具有挑战性的超分子组合.
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