第三种类型的干扰素受体的合成异构体需要TYK2来激活STAT

Emily V Mesev1, Emma G Guare1, Alexander Ploss1

  • 1Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.

概括

与I型干扰素不同的是,III型干扰素 (IFN-λ) 信号独立于氨酸激酶2 (TYK2). 这项研究表明,非正规的受体综合体可能会调解这种TYK2-独立的IFN-λ信号传递.

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