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A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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功能上完好无损但抗原上不同的DENV融合循环的演化.

Rita M Meganck1, Deanna Zhu2, Stephanie Dong2

  • 1Department of Molecular Microbiology and Immunology, Saint Louis University, Saint Louis, United States.

eLife
|September 19, 2023
PubMed
概括

研究人员设计了一种突变的登革热病毒 (DENV) 变种,以逃避抗体依赖增强,这是DENV疫苗面临的主要挑战. 这种修改后的DENV可能会为没有先前接触DENV的人提供更安全的疫苗.

关键词:
登革热病毒感染者进化 演化 演化 演化 演化 演化 演化 演化融合循环中的融合循环.传染病是一种传染性疾病.微生物学的微生物.和突变发生的原因是和突变.血液中的血清是血清.疫苗 疫苗 疫苗 疫苗病毒病毒病毒病毒.

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