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偏甲状腺切除术后复发性或持续性二次性偏甲状腺功能障碍症患者的射频切除:初始经验
Tingting Jiang1,2,3, Erya Deng1,2,3, Huihui Chai1,2,3
1Department of Medical Ultrasound, Center of Minimally Invasive Treatment for Tumor, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Endocrine
|September 19, 2023
概括
超声导向射频切除 (RFA) 提供了一种安全有效的微创治疗术后持续的二次性偏甲状腺症 (SHPT). 这种可重复的疗法显著改善了患者的症状和激素水平.
科学领域:
- 内分泌学 在内分泌学.
- 干预性放射学 干预性放射学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 由于痕和粘附,甲状腺切除术后的二次性甲状腺功能障碍症 (SHPT) 的重新手术是复杂的.
- 对于复发或持续的SHPT,需要进行最少的侵入性疗法.
研究的目的:
- 评估超声波 (US) 指导的射频除 (RFA) 在治疗复发性或持久性SHPT的疗效.
- 在这个患者群体中分析美国指导的RFA的安全性和可重复性.
主要方法:
- 十名患有复发性或持续性SHPT的患者在20个扩大的副甲状腺上接受了美国指导的RFA.
- 血清完整的副甲状腺激素 (iPTH),,和ALP水平被监测.
- 评估了临床症状和与程序相关的并发症.
主要成果:
- 血清iPTH,和水平在去除后显著下降.
- 70%的患者在六个月内达到目标IPTH水平; 50%在随访结束时.
- 观察到临床症状显著改善;主要并发症包括声和永久性副甲状腺功能障碍.
结论:
- 美国指导的穿皮RFA是一种安全,有效和可重复治疗复发性或持久性SHPT.
- RFA可以显著改善与甲状腺功能障碍相关的症状.
- 这种最少的侵入性方法解决了SHPT重新运行的挑战.
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