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一个随机试验,持续监测葡萄糖以改善移植后的血糖控制
Nicholas Jandovitz1, Sam J George2, Mersema Abate1
1Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, New York, USA.
Clinical transplantation
|September 19, 2023
概括
持续的葡萄糖监测通过减少高血糖,显著改善了移植患者的血糖控制. 这项技术提供了一种安全有效的方法,用于在移植后立即管理血糖.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 内分泌学 在内分泌学.
- 医疗器械 医疗器械
背景情况:
- 移植后高血糖是接受移植的患者常见的并发症.
- 有效的血糖管理对于优化移植结果和患者健康至关重要.
研究的目的:
- 评估连续血糖监测 (CGM) 与传统的指针监测相比,在成年移植接受者中对血糖控制的有效性.
- 评估CGM对高血糖和低血糖发作,细菌感染和停留时间的影响.
主要方法:
- 一个单位,前性随机受控试验,涉及40名患有糖尿病的成年移植接受者.
- 患者被随机分配,在移植后的前5天接受传统的指针血糖监测或CGM (Medtronic Guardian Sensor 3).
主要成果:
- 而CGM组的平均每日葡萄糖水平显著降低.
- 在CGM组中,在术后2-5天观察到显著较少的高血糖发作 (≥180 mg/dL).
- 在低血糖 (≤80 mg/dL),术后细菌感染或组间停留时间之间没有发现显著差异.
结论:
- 持续的葡萄糖监测有效地降低了高血糖,并在移植后的立即时期改善了血糖控制.
- 在这种情况下使用CGM不会增加低血糖或其他不良事件的风险.
- 在接受移植的患者中,CGM是管理葡萄糖水平的宝贵工具.
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