用机器学习和创新算法包容性承销乳腺癌风险的方法
Manuel Plisson1, Antoine Moll1, Valentine Sarrazin1
1SCOR Global Life, Knowledge Team, 5 Avenue Kléber, 75795 Paris Cedex 16, France.
Journal of insurance medicine (New York, N.Y.)
|September 19, 2023
概括
一个新的算法通过分析关键的病理因素来促进乳腺癌幸存者的承保. 后勤回归被证明是准确,包容的保险风险评估最有效的方法.
科学领域:
- 在瘤学瘤学.
- 生物统计学 生物统计学
- 医疗信息学 医疗信息学
背景情况:
- 越来越多的长期乳腺癌幸存者需要包容性的承保实践.
- 目前的承保方法可能无法充分解决乳腺癌幸存者的复杂问题.
- 越来越需要基于数据的方法来评估这一群体的风险.
研究的目的:
- 开发和评估一种算法方法,用于承销乳腺癌幸存者.
- 为了促进在有乳腺癌病史的个体中评估多种风险参数.
- 支持乳腺癌幸存者更准确,更包容的保险定价.
主要方法:
- 使用SEER数据库进行变量提取和分析.
- 我们比较了四种机器学习算法:物流回归,GA2M,随机森林和XGBoost.
- 使用AUC,Log Loss和SMR等指标评估算法性能,但不包括in situ和转移病例.
主要成果:
- 选择的参数包括病理亚型,pTNM分期,Scarff-Bloom-Richardson分级和激素受体状态.
- 所有测试的算法都显示了可比的统计性能 (AUC,日志损失,SMR).
- 逻辑回归被确定为最佳模型,因为它遵循业务约束和用户可理解性.
结论:
- 开发的算法可以提高乳腺癌幸存者的风险估计的准确性.
- 承保人友好的计算器可以合理化保险定价.
- 这种方法通过适应癌症异质性来支持更具包容性的保险承保.
更多相关视频
04:09Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma
Published on: October 10, 2018
8.3K
07:41Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
9.0K
相关概念视频
Cancer Survival Analysis
381
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
381
Adaptive Mechanisms in Cancer Cells
5.8K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.8K
