老年人中低血压和认知障碍:来自CLHLS的证据
Xidi Zhu1,2, Zhicheng Luo1, Gang Tian1
1Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
PloS one
|September 19, 2023
概括
低血压或低血压与中国老年人的认知障碍有关. 控制血压可能有助于预防这种人群的认知衰退.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 建立了高血压与认知衰退的联系.
- 低血压 (低血压) 和认知障碍之间的关联仍未得到充分研究,特别是在老年人群中.
研究的目的:
- 确定中国老年人中低血压和认知障碍的患病率.
- 在这个人口群体中调查低血压和认知功能之间的关系.
主要方法:
- 利用了2018年中国长度健康长寿调查 (CLHLS) 的数据.
- 客观地测量了静缩血压 (SBP) 和静缩血压 (DBP).
- 使用中国迷你精神状态检查 (CMMSE) 评估认知障碍.
- 采用了通用线性模型来分析低血压和认知障碍之间的关联.
主要成果:
- 在中国老年人中,低血压的患病率为0.76%,认知障碍的患病率为22.06%.
- 低血压,较低的SBP和较低的DBP与认知障碍的可能性增加有关 (OR分别为1.62,1.38,1.48).
- 在低血压和较低血压水平的人群中,CMMSE得分明显较低.
- 在那些日常生活活动减少的人群中,这种关联更强烈,并且观察到非线性剂量-反应关系.
结论:
- 低血压是中国老年人认知障碍的潜在危险因素.
- 那些日常生活活动减少和低血压的人特别容易受到伤害.
- 建议包括实施血压管理策略,以减轻认知能力下降.
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