在COVID-19疫苗接种后出现绝经后出血
Tia L Kauffman1, Stephanie A Irving1, Neon Brooks1
1Kaiser Permanente Center for Health Research, Portland, OR.
接种COVID-19疫苗并没有增加绝经后出血的诊断. 接种疫苗后新出现的出血很少见,大多数病例归因于其他原因,如子宫病变或激素治疗.
科学领域:
- 妇科 妇科 妇科 妇科
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 有限的数据存在于COVID-19疫苗接种后的绝经后出血.
- 疫苗接种后月经变化的研究主要集中在绝经前的个体上.
研究的目的:
- 分析COVID-19疫苗引入前后的绝经后出血诊断趋势.
- 为了描述COVID-19疫苗接种后出现的新发性绝经后出血病例.
主要方法:
- 从2018-2021年对发生的绝经后出血诊断 (≥45年) 的细分回归分析.
- 在COVID-19疫苗接种后60天内发生的绝经后出血病例的图表综述.
- 排除具有先前出血病或其他风险因素的个人.
主要成果:
- 在接种疫苗之前和之后的绝经后出血发生率没有显著差异 (P=.59).
- 在接种疫苗后60天内诊断出104例病例,76%的确诊为接种疫苗后出血.
- 常见的原因包括子宫/子宫病变 (50%),激素治疗 (13%) 和生殖性子宫内膜 (13%).
结论:
- 引入COVID-19疫苗与更年期后出血诊断的增加没有关联.
- 接种COVID-19疫苗后的绝经后出血是一个罕见的现象.
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