患有大麻依赖综合征的人的"非使用者"一级亲属的认知障碍:一个试点,内分类型研究
Shrayasi Das1, Lokesh Kumar Singh1, Sai Krishna Tikka2
1Department of Psychiatry, All India Institute of Medical Sciences (AIIMS), Raipur, India.
Early intervention in psychiatry
|September 19, 2023
概括
患有大麻依赖综合征的个人的一级亲属表现出认知障碍,特别是在口语流和记忆方面. 这些认知缺陷可能作为大麻依赖的特征标志物.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 遗传学 遗传学 是一个
背景情况:
- 大麻使用障碍是一个日益增长的全球健康挑战,具有显著的发病率.
- 在大麻依赖的个体中,经常观察到认知障碍和遗传脆弱性.
- 关于认知功能作为大麻依赖的内分类型的研究是有限的.
研究的目的:
- 为了研究大麻成中认知功能障碍的内类型模式.
- 检查患者及其亲属的认知功能与社会人口统计学/临床变量之间的关联.
主要方法:
- 一项比较研究涉及患有大麻依赖综合征的患者,他们的非使用者一级亲属和健康的对照组 (每组30名参与者).
- 评估五个认知领域:注意力,语言流,记忆力,视觉空间能力和执行功能.
- 使用克鲁斯卡尔-瓦利斯试验进行统计分析,并对多重比较进行校正,并进行相关性分析.
主要成果:
- 在一级亲属中观察到显著的认知障碍,特别是在口语流和口语记忆的所有子分数中.
- 患有大麻依赖症的患者也表现出注意力和执行功能受损.
- 认知障碍与社会人口统计学或临床变量之间没有发现显著的相关性.
结论:
- 大麻成的个人非使用者一级亲属表现出显著的认知障碍.
- 语言流和语言记忆被确定为大麻依赖综合征的潜在内分类型或特征标记.
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