一项对非常早产婴儿的产后人体成长和子宫内生长的比较研究
Fu-Sheng Chou1,2, Hung-Wen Yeh3,4, Reese H Clark5
1Department of Neonatology, Kaiser Permanente Riverside Medical Center, Riverside, CA, USA. Fu-Sheng.X.Chou@kp.org.
Nature communications
|September 19, 2023
概括
非常早产婴儿的产后生长与子宫内生长有很大的不同. 新的模型显示了不同的生长阶段,为临床评估和营养研究提供了实用的工具.
科学领域:
- 新生儿科学 新生儿科学
- 儿科生长与发展 儿科生长与发展
- 生物统计学 生物统计学
背景情况:
- 目前非常早产婴儿的生长参考通常依赖于出生测量,假设它们反映了子宫内生长.
- 美国儿科学会的目标是接近这些婴儿的子宫内生长率仍然不确定.
研究的目的:
- 开发模型来描述非常早产婴儿的产后生长模式.
- 为了比较这些产后生长模式与子宫内生长.
- 评估在非常早产婴儿的子宫内生长率近似的可实现性.
主要方法:
- 利用了2010年至2020年间出生于非常早产婴儿的现实世界测量数据.
- 开发模型来分析体重,长度和头周长的增长率.
- 将产后生长轨迹与已确定的子宫内生长数据进行比较.
主要成果:
- 确定了产后体重增长的三个不同阶段,在子宫内生长中没有观察到.
- 产后长度和头周长的增长率最初呈现缓慢,随后加快.
- 在整体产后和子宫内生长模式之间显示出显著的差异.
结论:
- 在非常早产婴儿的产后生长从根本上不同于子宫内生长.
- 虽然不代表最佳的生长,但开发的产后生长模型对于临床评估和营养研究有价值.
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