产后外围止痛和产后抑郁症在初生患者之间的关联:一项历史的队列研究
Sherry Jin1,2, Allana Munro3,4, Ronald B George5
1Department of Anesthesia, Humber River Hospital, Toronto, ON, Canada.
Canadian journal of anaesthesia = Journal canadien d'anesthesie
|September 19, 2023
概括
产后外周止痛 (LEA) 与初生患者产后抑郁症 (PPD) 的几率增加有关. 这挑战了LEA降低PPD风险的想法,突出了这种情况.
科学领域:
- 产科和妇科 产科和妇科
- 围产期心理健康 围产期心理健康
- 流行病学 流行病学
背景情况:
- 产前期疼痛与产后抑郁症 (PPD) 有关.
- 产后外周止痛 (LEA) 是分娩期间常见的干预措施.
- 对LEA对PPD风险的潜在影响需要进一步调查.
研究的目的:
- 调查产后外围止痛 (LEA) 与新生母患产后抑郁症 (PPD) 的风险之间的关联.
- 为了检查LEA是否会改变原发性患者中PPD的风险.
主要方法:
- 一项使用省级围产期数据库的历史队列研究.
- 纳入标准:在2004年至2018年期间生育出一个活生生的单独婴儿的原生儿患者.
- 基于随后怀孕的记录来确定PPD;用于分析的后勤回归.
主要成果:
- 总共有35,437名患者被分析; 67%的患者接受了LEA.
- 后发性病的发生率为3.7%.
- 接受LEA治疗的患者患PPD的几率增加 (调整后OR,1.29;95% CI,1.12至1.48).
结论:
- 产后外周止痛 (LEA) 与初生妇女产后抑郁症 (PPD) 的风险较高有关.
- 这一发现与LEA可能降低PPD风险的假设相矛盾.
- 强调了分娩干预和母亲心理健康之间的复杂关系.
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