作为多血管冠状动脉疾病的良好预测指标,心脂肪体积是冠状动脉疾病的良好预测指标
Eman S El Shahawy1, Asmaa A Hassan2, Mohamed S El Shahawy3
1Department of Cardiology, Faculty of Medicine (for girls), Al-Azhar University, Cairo, Nasr city, 11651, Egypt. alshahawy1071979@yahoo.com.
在患有阻塞性冠状动脉疾病 (CAD) 的患者中,心上脂肪体积 (EFV) 显著增加. 增加EFV是阻塞性CAD和多血管疾病的独立预测因子.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 副心脏脂肪组织 (EAT) 在冠状动脉疾病 (CAD) 病原发生过程中发挥作用.
- 量化心上脂肪体积 (EFV) 可能为CAD提供了洞察力.
- 了解EFV和CAD严重程度之间的关系至关重要.
研究的目的:
- 调查心上脂肪体积 (EFV) 与阻塞性和多血管性心脏病的存在之间的关联.
- 确定EFV是否是阻塞性CAD的独立预测因素.
- 评估EFV对多血管疾病的预测价值.
主要方法:
- 这是一项对87名怀疑患有CAD的成年人进行的观察性研究.
- 用多探测器计算机断层扫描 (MDCT) 量化的心上脂肪体积 (EFV).
- 冠状动脉狭窄通过侵入性冠状动脉血管学 (ICA) 评估.
主要成果:
- 患有阻塞性CAD的患者EFV显著更高 (57 ± 20.14 cm3对比44 ± 7.4 cm3;P < 0.001).
- 在多血管疾病病例中EFV显著增加 (74 ± 24.3毫升 vs 53 ± 16.2毫升;P < 0.003).
- 多变量分析确定EFV是阻塞性CAD的一个独立风险因素 (OR,1.062;P < 0.005).
结论:
- 心上脂肪体积 (EFV) 的增加与阻塞性CAD有显著的关联.
- EFV是阻塞性CAD的独立预测因素,无论传统的风险因素和冠状动脉分数如何.
- EFV是多血管疾病发生的有价值预测指标.
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