功能跟踪心血管磁共振显示,在急性心肌炎后,心房功能恢复
J N Schneider1, C Jahnke2, E Cavus2
1Department of Cardiology, University Heart and Vascular Center Hamburg, Martinistrasse 52, 20246, Hamburg, Germany. j.schneider@uke.de.
The international journal of cardiovascular imaging
|September 19, 2023
概括
在急性心肌炎后的随访对于评估心脏功能至关重要. 这项研究表明,通过心血管磁共振特征追踪应变分析测量心房功能,在急性心肌炎后三个月显著改善.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 心血管疾病 心血管疾病
背景情况:
- 急性心肌炎可能导致持续的心肌功能障碍,需要定期随访.
- 在急性心肌炎后,心房功能的恢复尚未先前评估.
- 评估心房功能恢复对于全面了解心肌炎治愈非常重要.
研究的目的:
- 评估急性心肌炎后左心房 (LA) 和右心房 (RA) 功能的恢复.
- 用心血管磁共振 (CMR) 特征追踪 (FT) 应变分析来评估心房功能.
- 确定心肌病样心肌炎 (CLM) 和心脏病样心肌炎 (ILM) 呈现之间心房功能恢复是否有差异.
主要方法:
- 35名患有严格定义的急性心肌炎的患者在基线和3个月的随访期间接受了CMR (1.5 T).
- 根据临床表现和活检,患者被分为CLM (n=13) 和ILM (n=22) 亚组.
- 应用CMR特征追踪 (FT) 对传统电影序列来分析LA全球纵向菌株 (LA-GLS) 和RA全球纵向菌株 (RA-GLS).
主要成果:
- 在整个队列中,LA-GLS的中位数从基线 (33.2%) 到随访 (37.0%,P=0.0018) 显著增加.
- 在整个队列中,中位数RA-GLS也从基线 (30.8%) 到随访 (33.7%,P=0.0027) 显著增加.
- 在随访时,LA-GLS和RA-GLS在ILM和CLM分组均显示出显著的改善,这表明无论临床表现如何,心房功能都恢复了.
结论:
- 心血管磁共振特征跟踪应变分析显示,急性心肌炎后三个月,左心房和右心房功能显著恢复.
- 耳前功能恢复发生在临床表现 (ILM与CLM) 独立的情况下.
- 通过CMR-FT监测心房应变可能成为个性化评估治疗后急性心肌炎的有价值工具.
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