基于长期结果的BVO-ME治疗策略,通过OCT图像和视觉敏度对视网膜结构进行相关联
Yuki Hattori1, Ryo Fujiwara2, Hidetsugu Mori2
1Department of Ophthalmology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka, 573-1191, Japan. hattoyuk@hirakata.kmu.ac.jp.
BMC ophthalmology
|September 19, 2023
概括
完整的视网膜结构,如EZ带和凸,对视网膜静脉封闭的患者来说,长期预测更好的视力敏度. 经常出现的脑下液会对视力产生负面影响,强调需要持续治疗.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 血管医学 血管医学
背景情况:
- 内抗血管内皮生长因子 (VEGF) 注射是治疗分支视网膜静脉封闭 (BVO-ME) 继发的黄斑的标准.
- 现有的研究主要集中在针对BVO-ME的抗VEGF治疗的短期结果上.
- 对于BVO-ME视觉结果的长期预后指标仍未得到充分研究.
研究的目的:
- 为了识别BVO-ME患者的视觉预后的长期指标,这些患者接受了内抗VEGF治疗.
- 调查视网膜结构完整性之间的相关性,通过光学一致性断层扫描 (OCT) 评估,和长期视力敏度.
主要方法:
- 在堪萨伊医科大学医院 (2012年6月 - 2022年3月) 用内抗VEGF治疗的BVO-ME患者的回顾性分析.
- 纳入标准:抗VEGF的第一线治疗,至少36个月的随访.
- 排除标准:其他眼部疾病,先前的BVO-ME治疗. 根据最终最佳校正视敏度 (BCVA) 分类的患者.
主要成果:
- 分析了45名患者的47只眼睛,平均随访时间为64.38个月.
- 带有完整的EZ带和凸的眼睛显示出明显更好的视力敏度.
- 在具有更好的长期视觉结果的眼睛中观察到下液 (SRD) 的复发率较低.
结论:
- 在BVO-ME.中,EZ带和凸的完整性是长期视力敏度的重要预测指标.
- 复发性SRD与较差的长期视觉预后有关,即使最初的视力敏度很好.
- 长期的结构完整性对于BVO-ME.的持续视觉功能至关重要.
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