在5个欧洲国家,金黄色葡萄球菌手术部位感染率
Sibylle C Mellinghoff1,2,3, Caroline Bruns4,5,6, Markus Albertsmeier7
1Department I for Internal Medicine, Excellence Centre for Medical Mycology (ECMM), University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. Sibylle.mellinghoff@uk-koeln.de.
Antimicrobial resistance and infection control
|September 19, 2023
概括
在欧洲中心,黄金葡萄球菌 (S. aureus) 手术部位感染 (SSI) 的总发病率很低,为0.4%. 这项研究展示了在医疗保健相关感染流行病学中进行大数据分析的半自动化方法.
科学领域:
- 传染病流行病学 传染病流行病学
- 手术部位感染 手术部位感染
- 公共卫生 公共卫生
背景情况:
- 手术部位感染 (SSI) 对患者安全和医疗保健系统构成重大威胁.
- 黄金葡萄球菌 (S. aureus) 是一种常见的致病原体,导致SSI,对抗生素的敏感性各不相同.
- 了解S. aureus SSI的发病率和风险因素对于有效的预防策略至关重要.
研究的目的:
- 确定欧洲所有手术学科中S. aureus SSI的整体和程序特定发病率.
- 为了确定与S. aureusSSI相关的风险因素.
- 评估一个半自动化方法大数据分析在医疗保健相关感染流行病学.
主要方法:
- 2016年在14个欧洲中心进行手术的患者的回顾性队列研究.
- 嵌套病例控制分析使用倾向得分匹配.
- 细菌学和电子健康记录数据的半自动交叉匹配用于识别S. aureus. SSI.
主要成果:
- 在178,902名患者中,共发现了764例S. aureus SSI病例,导致整体发病率为0.4%.
- 大多数S. aureusSSI (86.0%) 是由甲素敏感菌株引起的,而14%是由甲素耐药菌株引起的.
- 平均S. aureus SSI发病率在所有外科专业中是一致的,但根据特定的外科手术程序有显著差异.
结论:
- 在这个大规模的,独立于程序的欧洲队列中,金黄色细菌SSI的总体发病率很低 (0.4%).
- 该研究验证了一种半自动化大数据方法,用于对医疗保健相关感染的流行病学监测.
- 对特定程序的风险因素进行进一步的研究是有必要的,以完善预防工作.
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