用于治疗应用的活性氧物种:压电材料的作用
Dipanjan Sengupta1,2, Sudip Naskar1, Dipankar Mandal1
1Quantum Materials and Devices Unit, Institute of Nano Science and Technology, Knowledge City, Sector81, Mohali 140306, India. dmandal@inst.ac.in.
Physical chemistry chemical physics : PCCP
|September 20, 2023
概括
压电材料产生反应性氧物种 (ROS) 用于疾病治疗. 超声波增强了这种效果,为瘤,感染和神经系统疾病提供了向治疗.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术 纳米技术
- 医学化学 医学化学
背景情况:
- 反应性氧物种 (ROS) 在体内补救疗法中起着至关重要的作用.
- 压电材料具有独特的非中心对称性,可以在机械刺激下产生ROS.
- 对于有针对性的治疗应用,可以利用ROS的反应性.
研究的目的:
- 突出压电材料驱动的ROS生成的治疗潜力.
- 探索压电材料和超声波的联合效应,以提高ROS生产.
- 审查压触媒材料在各种疾病中的应用.
主要方法:
- 讨论压电材料的特性及其在ROS生成中的作用.
- 对用于治疗应用的压电材料与超声波相结合的研究的综述.
- 用于ROS分析的光谱光度计方法的描述.
主要成果:
- 压电材料,当机械刺激时,产生具有高特异性的ROS.
- 超声波可以远程触发压电材料以产生用于治疗目的的ROS.
- 压触媒材料在治疗瘤,细菌感染,牙科问题和神经系统疾病方面表现有前途.
结论:
- 基于压电材料的ROS生成提供了一个有前途的治疗策略.
- 需要进一步的研究来应对挑战,并优化基于压电材料的疗法.
- 这种方法具有针对性治疗各种疾病的潜力.
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