左心房功能指数预测急性心肌梗塞患者接受皮肤冠状动脉干预治疗的结果不佳
Yijin Tang1, Siling Peng1, Hui-Ling Yao2
1Department of Cardiology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Frontiers in cardiovascular medicine
|September 20, 2023
概括
左心房功能指数 (LAFI) 可以预测经皮冠状动脉干预 (PCI) 的急性心肌梗塞 (AMI) 患者的不良事件. 较低的LAFI值表明心血管不良事件的风险更高,有助于患者风险分层.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心血管研究研究心血管研究
背景情况:
- 在接受皮肤冠状动脉干预 (PCI) 治疗的急性心肌梗塞 (AMI) 患者中,左心房功能指数 (LAFI) 的预后意义仍然不清楚.
- 拉菲集成左心房空分数,调整左心房体积和中风体积.
研究的目的:
- 调查LAFI对经过PCI的AMI患者预后的预测价值.
- 确定LAFI是否可以用于该患者群体的风险分层.
主要方法:
- 预期招募368名用PCI治疗的AMI患者.
- 在基线和随访时进行的跨胸腔心声扫描 (TTE).
- 终点事件包括因心痛不稳定而重新住院,非致命的心肌梗塞,心力衰竭和心血管死亡.
主要成果:
- 经历终点事件的患者与没有事件的患者相比,LAFI显著降低 (34.25 ± 12.86比48.38 ± 19.42,P < 0.0001).
- 多变量考克斯分析确定LAFI (HR=0.97;P=0.012) 和基利普分类 (HR=1.51;P=0.034) 作为不良事件的独立预测因素.
- 卡普兰-梅尔分析显示,LAFI ≤ 40.17 cm/ml/m2 (HR=8.53;P < 0.0001) 的患者的事件发生率显著更高.
结论:
- 左心房功能指数 (LAFI) 是PCI治疗的AMI患者不良心血管事件的强大和独立预测指标.
- 在这种患者队列中,LAFI可以有效地用于风险分层,指导临床管理.
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