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开发一种简短的认知查工具,用于预测帕金森病患者手术后 Delirium:二次分析

Yongde Zhou¹, Xiaoxiao Wang^2,3, Zhengqian Li^2,4

¹Department of Anesthesiology, Tsinghua University Yuquan Hospital, Beijing, 100040, People's Republic of China.

Clinical interventions in aging

|September 20, 2023

概括

缩短的认知测试,迷你心理状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA),有效地预测帕金森病患者的手术后妄 (POD). 这些快速评估适用于繁忙的手术前环境.

科学领域:

神经学神经学
老年病的医生老年病的医生
医学诊断医学诊断医学诊断

背景情况:

需要在资源有限,快节奏的手术前环境中进行快速认知查测试.
接受手术的帕金森病 (PD) 患者有患术后妄想症 (POD) 的风险.

研究的目的:

开发和验证小型心理状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA) 的缩写版本.
评估这些简短的认知测试在预测计划进行手术的PD患者中POD的有用性.

主要方法:

对128名PD住院患者进行的二次分析,这些患者接受了亚thalamic核深度大脑刺激 (STN-DBS).
使用MMSE和MoCA进行手术前认知查;通过混评估方法评估POD.
使用了后勤回归和接收器操作特征 (ROC) 曲线分析 (DeLong测试).

主要成果:

在128名PD患者中,有27名 (21.6%) 患有POD.
减少的MMSE显示出与原始MMSE (p=0.412) 相似的POD预测性能.
简短的MoCA显示了ROC曲线下的高面积 (AUC=0.826),与原来的MoCA (AUC=0.808,p=0.575) 相比.

结论:

简化的MMSE和MoCA版本可以有效地识别患有POD风险的PD患者.
简短的认知查测试对于在时间有限的手术前环境中预测POD是有价值的.

关键词:

蒙特利尔的认知评估帕金森病是帕金森氏症的一种疾病.迷你精神状态考试精神状态考试术后妄症术后妄症在手术前的认知障碍.

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