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使用IDEAL-IQ序列的肝脏MRI成像:Gd-EOB-DTPA是否会干扰脂肪分数量化的繁殖能力?

Yuan Tian¹, Peng-Fei Liu¹, Jia-Yu Li¹

¹Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.

World journal of clinical cases

|September 20, 2023

概括

加多克酸二对比剂不会影响使用水和脂肪的代分解与回声不对称和最小平方估计量化序列 (IDEAL-IQ) 的肝脂肪分数测量. 这种技术具有很高的可重现性,可以进行高效的多相检查.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
肝病学肝病学是一种肝病学.

背景情况:

水和脂肪的代分解与回声不对称和最小平方估计量化 (IDEAL-IQ) 是一种基于化学移位的技术,用于测量质子密度脂肪分数.
之前的研究证实了IDEAL-IQ对肝脂肪评估的准确性和可重复性.

研究的目的:

为了确定加多克酸二 (Gd-EOB-DTPA) 的对比剂是否会干扰肝脏脂肪含量的IDEAL-IQ测量.
在Gd-EOB-DTPA的存在下评估IDEAL-IQ技术的稳定性.

主要方法:

IDEAL-IQ被用来量化肝脏脂肪含量在3.0T在65名患者后Gd-EOB-DTPA注射.
肝脏脂肪分数 (FF) 和R2* 在前对照,门口,延迟和肝胆阶段进行测量.
单向重复措施分析和布兰德-阿尔特曼地块评估了FF的一致性和变化.

主要成果:

在肝脏,脏和脊柱的四个时间点中,没有观察到FF的显著差异.
肝脏FF测量显示时间点之间的高一致性 (95%CI在±0.68%以内).
肝脏,脏和脊柱的R2*值在对比后显著增加 (P < 0.0001).

结论:

肝脏脂肪分量的IDEAL-IQ测量没有受到Gd-EOB-DTPA的显著影响.
IDEAL-IQ的高可重现性支持其在多相检查中的使用,以提高时间效率.

关键词:

增强磁共振成像技术增强磁共振成像技术脂肪分数脂肪分数达多克塞酸二水和脂肪的代分解与回声不对称性和最小平方估计量化序列的量化序列.R2* 是一个R2* 类型.

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