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Updated: Jul 16, 2025

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
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Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes

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一种托兰修饰的5-乙氨基里丁作为一种通用和的光化学DNA交叉连接剂

Hermann Neitz1, Claudia Höbartner1,2

  • 1Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. claudia.hoebartner@uni-wuerzburg.de.

Chemical communications (Cambridge, England)
|September 20, 2023
PubMed
概括

研究人员开发了一种光核酸盐,Tol dU,用于光响应DNA交联. 这种方法使得DNA聚合物组装和序列检测具有增强的光,推进DNA纳米技术应用.

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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