相关实验视频
Updated: Jul 16, 2025

09:58
Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
11.7K
通过使用超高分辨率质谱法进行帕特诺-布奇反应对烯酸的选择性表征
Wenya Hu1, Jialin Niu1, Ruoning Bao1
1State Key Laboratory of Heavy Oil Processing, China University of Petroleum-Beijing, Beijing 102249, P. R. China.
Analytical chemistry
|September 20, 2023
概括
这项研究引入了一种使用帕特诺-布奇 (PB) 反应和大气压力化学电离-超高分辨率质谱法 (APCI-UHRMS) 分析石油油脂的新方法. 该技术可以在复杂样本中更好地检测到这些关键的工业化合物.
科学领域:
- 石油化学 石油化学
- 分析化学 分析化学
- 有机化学 有机化学
背景情况:
- 石油油脂是化学工业中必不可少的原料.
- 分析复杂的烯混合物,特别是较重的分数,由于电离难度和矩阵复杂性,传统质谱具有挑战性.
- 目前的方法往往难以选择性地描述石油中的多种烯结构.
研究的目的:
- 开发一种选择性和高效的分析方法来表征石油烯,特别是超出典型气相色谱范围的石油烯.
- 为了克服软电离和矩阵复杂性的局限性,在质谱分析中分析烯酸.
- 为了实现重型石油样品的全面分子分析,以优化工艺.
主要方法:
- 采用帕特诺-布基 (PB) 反应,将烯CC键衍生为更多极性氧化环.
- 用大气压化学电离加上超高分辨率质谱法 (APCI-UHRMS) 来分析衍生烯酸.
- 对PB反应条件和APCI-UHRMS参数进行了优化,以最大限度地提高反应产量和质谱反应.
主要成果:
- 帕特诺 - 布基反应成功地改善了olefins的极性,促进了软电离.
- 建立了一个强大的分析方案,以区分共存的不和基,包括线性和非线性烯酸,环基和芳香物.
- 该方法在分析复杂流体催化裂变油泥样本中的烯酸中显示出高效率和选择性.
结论:
- 开发的PB反应与APCI-UHRMS相结合,为选择性分析石油烯提供了强大的工具.
- 这种方法扩大了在重石油样本中表征更广泛的烯酸的能力,为更全面的分子图书馆做出了贡献.
- 该方法在推进石油工艺优化和理解复杂的碳化合物矩阵方面具有重大潜力.
相关概念视频
High-Resolution Mass Spectrometry (HRMS)
1.4K
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
1.4K
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
1.1K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.1K
Mass Spectrometry: Branched Alkane Fragmentation
1.1K
This lesson delves into the mass spectrometry of branched alkane fragmentation. Branched alkanes possess secondary or tertiary carbon atoms, which generate relatively stable carbocations if the cleavage occurs at the branching point. The high stability of carbocations drives the instant fragmentation of branched alkanes. Accordingly, the branched alkane's molecular ion peak is very weak or invisible in the mass spectra, especially in comparison to a linear alkane.
1.1K
Mass Spectrometry: Molecular Fragmentation Overview
3.2K
The ionization of a molecule into a molecular ion inside the mass spectrometer causes instability in the molecule's structure due to the loss of an electron. This eventually leads to the fragmentation or breaking of some bonds in the molecule. The fragmentation occurs predominantly at specific bonds to yield relatively stable fragments.
One type of fragmentation pattern is the cleavage of a single bond in the molecular ion. The cleavage leads to a radical and a cation. The cleavage can...
One type of fragmentation pattern is the cleavage of a single bond in the molecular ion. The cleavage leads to a radical and a cation. The cleavage can...
3.2K
Mass Spectrometry: Long-Chain Alkane Fragmentation
1.7K
The molecular ions of linear alkanes prefer to fragment at the carbon-carbon bond away from the end of the chain since the cleavage of an inner bond creates a stable carbocation and a stable radical. Consequently, the mass signals of linear alkanes feature intense peaks in the middle of the mass-to-charge ratio plot with weaker peaks on either end. The fragmentation of each carbon-carbon bond with the release of a methyl group in each splitting leads to prominent peaks in the mass spectra...
1.7K
Mass Spectrometry: Cycloalkane Fragmentation
1.4K
In mass spectrometry, cycloalkanes exhibit distinct fragmentation patterns due to the inherent stability of their molecular ions compared to linear or branched alkanes. The ring structure of cycloalkanes provides additional stability to the molecular ions, often resulting in prominent ion peaks in the mass spectrum.
For example, cyclohexane molecular ions have a mass-to-charge ratio (m/z) of 84, which tends to produce a stronger signal than linear alkanes like hexane. This stability comes from...
For example, cyclohexane molecular ions have a mass-to-charge ratio (m/z) of 84, which tends to produce a stronger signal than linear alkanes like hexane. This stability comes from...
1.4K

