肝移植接受者的疼痛治疗方法
Simrat Kaur1, Patrick Henthorn, Adrian Hendrickse
1Department of Anesthesiology, University of Colorado, Aurora, Colorado, USA.
Current opinion in organ transplantation
|September 20, 2023
概括
由于药物代谢变化和阿片类药物滥用高风险,肝移植患者的疼痛管理是复杂的. 最佳的疼痛控制需要采用多模式的方法,在必要时考虑区域麻醉的替代方案.
科学领域:
- 麻醉学 麻醉学
- 肝病学 肝病学是一种肝病学.
- 疼痛管理 疼痛管理
背景情况:
- 肝移植接受者面临着独特的疼痛管理挑战.
- 末期肝病会影响药物代谢和清除.
- 凝血病和血小板缺血限制了区域麻醉的选择.
- 药物使用障碍的高患病率增加了阿片类药物滥用风险.
研究的目的:
- 审查肝移植接受者的最佳疼痛管理策略.
- 讨论这个患者群体的疼痛管理方面的挑战.
- 介绍当前关于术后疼痛控制的基于证据的文献.
主要方法:
- 基于证据的研究的文献综述.
- 对肝移植患者疼痛管理策略的分析.
- 评估区域麻醉技术和药理干预措施.
主要成果:
- 胸腔外围注射可以在正常凝血的特定情况下提供更好的疼痛控制.
- 骨干阻塞和腹部伤口导管是凝血病患者的可行的替代方案.
- 建议使用涉及专业团队的多模式疼痛管理.
结论:
- 胸腔外周止痛是一种潜在的选择,用于肝移植的接受者与正常的凝血.
- 应考虑替代区域技术,当外围注射器是禁忌的.
- 优化多式止痛药和非药物干预措施至关重要.
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