在患有肺高血压的儿童中出现睡眠呼吸障碍
Daniel Ignatiuk1,2, Kimberley Miles2,3, Neepa Gurbani1,2
1Cincinnati Children's Hospital Medical Center, Division of Pulmonary and Sleep Medicine, Cincinnati, Ohio, USA.
Pediatric pulmonology
|September 20, 2023
概括
阻塞性睡眠呼吸暂停 (OSA) 在患有肺高血压 (PH) 的儿童中很常见,89%的儿童被诊断为. 建议对这些儿童进行常规的睡眠呼吸障碍 (SDB) 查,使用多睡眠学 (PSG).
科学领域:
- 儿科肺病学 儿科肺病学
- 睡眠医学 睡眠医学
- 心脏病学 心脏病学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 和肺高血压 (PH) 具有复杂的双向关系.
- 儿童PH中OSA和其他睡眠呼吸障碍 (SDB) 的患病率尚不清楚.
- 了解儿科PH中的SDB可以为诊断和治疗策略提供信息.
研究的目的:
- 确定PH儿童中SDB共诊断的比例.
- 在儿科PH队列中识别OSA风险因素.
- 根据PH分类来评估其他SDB诊断的发生情况.
主要方法:
- 从2010年到2020年,对患有PH的儿童 (0-21岁) 进行过多睡眠图 (PSG) 的回顾性图表审查.
- 主要结局:OSA发生率和风险因素 (人口统计,诊断,PH分类).
- 二次结果:基于PH分类的其他SDB诊断和风险.
主要成果:
- 在89% (79/89) 的儿童中诊断出OSA;其他SDB在很大比例.
- 三重症21与增加的OSA风险相关 (RR:1.24).
- 年龄>12个月在PSG与OSA风险降低相关 (RR:0.60);没有SDB风险差异PH组.
结论:
- 大多数PH儿童患有OSA,许多儿童有其他SDB诊断.
- 这些发现支持在PH儿童中与PSG进行常规SDB查.
- 早期发现和管理SDB可能会改善儿科PH的结果.
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