带有编织内膜桥装置的血栓栓塞事件:发生率,预测因素和管理
Fernanda Rodriguez-Erazú1,2, Jonathan Cortese1,3, Cristian Mihalea1
1Department of Interventional Neuroradiology, Bicêtre University Hospital, Paris , France.
Neurosurgery
|September 20, 2023
概括
血栓栓塞栓事件 (TEE) 发生在13%的Woven EndoBridge (WEB) 设备治疗宽动脉瘤的患者中. 破裂动脉瘤和设备更换预测TEEs,但管理产生最小的发病率.
科学领域:
- 神经外科 神经外科
- 干预性神经放射学 干预性神经放射学
- 血管外科 血管外科
背景情况:
- 编织EndoBridge (WEB) 设备越来越多地用于宽动脉瘤.
- 虽然有效,但已报告有显著的血栓栓塞事件 (TEE) 发生率.
- 预测因素和TEE的管理需要进一步阐明.
研究的目的:
- 为了评估TEE的发病率和管理在WEB设备治疗后.
- 在破裂和未破裂的内动脉瘤中确定TEE的预测因素.
- 评估 WEB 器件栓塞的临床结果和安全性.
主要方法:
- 用WEB设备治疗动脉瘤的单中心数据库的回顾性审查 (2012年7月 - 2022年5月).
- 分析包括手术内和延迟的TEE.
- 进行了单变量和多变量分析,以确定TEE预测因素.
主要成果:
- 总共治疗了266例动脉瘤;13% (35/266) 经历了TEE,其中8.7%是手术内.
- 带有临床后果的症状TEE发生在2.6% (7/266) 的患者中,没有TEE相关的死亡率.
- 破裂动脉瘤 (aOR=2.74) 和WEB设备更换 (aOR=2.61) 是TEE的独立预测因素.
结论:
- 破裂动脉瘤和手术内替换器件是TEE的重要预测因素.
- 仔细选择 WEB 设备对于最佳治疗结果至关重要.
- 有效的TEE医疗管理,包括使用蒂罗菲班,可以实现最小的发病率和无死亡率,支持WEB技术的安全性.
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