相关实验视频

Updated: Jun 17, 2026

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

Published on: July 9, 2014

在血样本中量化细胞巨乳病毒DNA的Alinity m CMV试验的多中心性能评估

Miae Lee¹, Eliseo Albert², Els Wessels³

¹Ewha Womans University College of Medicine , Seoul, Republic of Korea.

Journal of clinical microbiology

|September 20, 2023

概括

准确的细胞巨乳病毒 (CMV) 病毒载量监测对于免疫功能低下的患者至关重要. Alinity m CMV测定显示出强大的分析和临床性能,提供快速结果,以指导及时的治疗决策.

科学领域:

临床诊断临床诊断临床诊断
病毒学病毒学
免疫受损患者的护理

背景情况:

细胞巨乳病毒 (CMV) 病毒载量监测对于管理免疫功能低下个体的感染和重新激活至关重要.
及时的治疗决定取决于准确的病毒载量量化.

研究的目的:

评估Alinity m CMV测定的分析和临床性能.
评估其在临床实验室环境中对CMV病毒载量监测的有用性.

主要方法:

分析性能使用六人小组进行评估.
临床性能通过比较Alinity m CMV与实时CMV和实验室开发的测试 (LDT) 在三家医院实验室进行评估.
测试了457个血样本.

主要成果:

性mCMV测定显示出极佳的精度 (SD 0.08-0.28日志IU/mL).
观察到与比较试验的高相关性 (r ≥0.942).
平均偏差范围从-0.03到0.34日志单位/毫升.
飞机上转机时间的中位数低于3小时.

结论:

该Alinity m CMV测定提供可靠和快速的CMV病毒载量量化.
它的性能支持其在临床环境中用于及时的患者管理.
该试验有可能缩短结果的时间,并更快地开始治疗.

关键词:

它们是DNA DNA DNA DNA.高通量诊断测定高通量诊断测定免疫性受损的人.核酸放大试验的核酸放大试验移植移植移植移植

更多相关视频

Optimization of a Quantitative Micro-neutralization Assay

Optimization of a Quantitative Micro-neutralization Assay

Published on: December 14, 2016

Author Spotlight: Addressing Regulatory Gaps in Molecular Studies by Quantifying Viral Vectors in Complex Matrices

Author Spotlight: Addressing Regulatory Gaps in Molecular Studies by Quantifying Viral Vectors in Complex Matrices

Published on: July 14, 2023

相关概念视频

Cytomegalovirus Disease

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...