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一种基于1,8-纳夫塔利米德的化学传感器用于细胞内和生物流体中检测Pd2+离子:显微镜和防伪研究

Sanjeev Kumar¹, Neha Sharma², Satwinder Singh Marok³

¹Department of Chemistry, UGC Centre for Advanced Studies-II, Guru Nanak Dev University, Amritsar 143001, Punjab, India. prabhpreet.chem@gndu.ac.in.

Analytical methods : advancing methods and applications

|September 20, 2023

概括

一种基于纳夫他胺的新型化学传感器 (NPG) 以高灵敏度检测离子 (Pd2+). 这种传感器显示出安全油墨和生物成像应用的潜力.

科学领域:

化学传感器化学传感器
材料科学材料科学材料科学
分析化学分析化学

背景情况:

纳夫塔利米德衍生物是有效的光剂.
开发对金属离子有选择性和敏感的化学传感器至关重要.
离子在催化和生物系统中起着重要的作用.

研究的目的:

开发一种基于纳夫他胺的化学传感器 (NPG),用于选择性检测离子 (Pd2+).
调查NPG的传感机制和性能.
探索NPG在生物和防伪背景中的适用性.

主要方法:

基于纳夫他胺的化学传感器 (NPG) 的合成和特征.
用光谱分析 (光,UV-Vis) 来研究NPG-Pd2+相互作用.
动态光散射 (DLS),扫描电子显微镜 (SEM) 和原子力显微镜 (AFM) 用于聚合研究.
细胞成像和样本分析 (药品,尿液,血清).

主要成果:

在Pd2+结合时,NPG表现出聚合诱导的排放增强 (AIEE) 和复合诱导的聚合引起的火 (ACQ).
在Pd2+的低检测极限 (LOD) 达到了75nM.
NPG在MG-63细胞中成功检测细胞内细胞,并在生物和制药样本中准确量化.
NPG显示出作为防伪安全墨水的潜力.

结论:

NPG是一种高效的Pd2+检测化学传感器,具有出色的灵敏度和选择性.
传感器的机制涉及复杂化诱导的聚合火.
NPG具有广泛的适用性,包括生物成像,样本分析和安全功能.

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