相关实验视频

Updated: Jul 16, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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格式补充增强抗瘤CD8+T细胞适应性和PD-1阻断的有效性

Jared H Rowe1,2,3, Ilaria Elia4,5, Osmaan Shahid2,3

  • 1Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

Cancer discovery
|September 20, 2023
PubMed
概括

用甲酸盐补充单碳 (1C) 代谢,可以增强CD8+T细胞功能,并改善抗PD-1免疫疗法对B16-OVA瘤的疗效. 这种方法克服了瘤微环境中的代谢限制,促进T细胞活性和瘤控制.

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Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells09:32

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

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