抗抑郁药使用对腹手术后手术后减肥的影响
相关实验视频
Updated: Jul 16, 2025

07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
23.6K
Sinead Haugh1, Paul Cromwell2, Richelle Kirrane3
1Department of Psychiatry, Blanchardstown Mental Health Services, Connolly Hospital, Blanchardstown, Dublin, West, Ireland. sineadmhaugh@gmail.com.
Irish journal of medical science
|September 20, 2023
概括
抗抑郁药的使用,特别是那些具有中等体重增加风险的药物,与减肥手术后一年的总体重减轻有关. 建议由专家进行仔细的药物管理,以获得最佳的患者结果.
科学领域:
- 腹部外科 腹部外科
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗抑郁药物药物经常与体重增加有关.
- 优化减肥手术的结果需要仔细考虑处方药.
- 在接受减肥手术的患者中,同时出现的精神疾病很常见.
研究的目的:
- 为了研究抗抑郁药的使用之间的联系,按体重增加风险分层,和体重减轻结果1年后腹部外科手术.
- 为了确定特定的抗抑郁药类是否影响减肥手术后的总体重减轻 (TWL).
主要方法:
- 在2018年7月至2021年期间,对315名接受减肥手术的患者进行了回顾性分析.
- 根据体重增加风险分层使用抗抑郁药;对照组没有使用抗抑郁药.
- 主要结局:6周,6个月和12个月的TWL%;用于12个月分析的多变量线性回归.
主要成果:
- 70名患者 (22.2%) 服用抗抑郁药.
- 接受中等风险体重增加抗抑郁药的患者在12个月后的TWL平均百分比显著下降 (p=0.015).
- 整体抗抑郁药的使用不是12个月后TWL%的显著预测因素 (p=0.0836).
结论:
- 减肥手术中的心理药物管理患者可能会从专家的投入中受益,例如减肥精神科医生.
- 解决心理健康和手术结果之间的复杂相互作用至关重要.
- 个性化药物治疗策略可以帮助优化腹腔外科手术后的减肥和患者整体福祉.
相关概念视频
Antidepressant Drugs: MAOIs and Other Agents
270
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
270
Antidepressant Drugs: Overview
555
Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
555
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
112
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
112
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
431
Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
431
The Placebo Effect
6.2K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.2K
Peripheral Artery Disease V: Postoperative Nursing Management
12
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
12

