美国和欧盟学术动物课程的比较:组织,运作和提供的服务
Patricia Preisig1, James D Macy2, Jann Hau3
1Departments of Medicine and Cellular and Molecular Physiology, Yale University, USA.
Laboratory animals
|September 20, 2023
概括
这项研究比较了美国和欧洲的学术动物研究中心. 欧洲中心通常在内部管理繁殖,更频繁地提供冷保存服务,并为动物殖民地维持更高的卫生标准.
科学领域:
- 动物研究设施管理比较动物研究设施管理.
- 实验室动物科学实验室动物科学
- 学术研究基础设施学术研究基础设施
背景情况:
- 耶鲁大学的动物资源成本和基准调查为评估美国学术动物研究/资源中心 (ARC) 提供了一个模型.
- 通过调整这项调查,可以对欧洲研究大学联盟 (LERU) 和相关机构内的学术ARC进行比较分析.
研究的目的:
- 为欧洲学术ARC (LERU成员) 进行调整和管理调查,以收集与美国ARC可比的数据.
- 确定和比较美国和欧洲学术动物研究中心之间的关键运营,财务和健康相关差异.
主要方法:
- 修改耶鲁大学对欧洲学术ARC进行的动物资源成本和基准调查.
- 从丹麦,英格兰,芬兰,法国,德国,爱尔兰,意大利,荷兰,苏格兰,西班牙和瑞士的参与机构收集数据.
- 对调查数据的分析,以确定美国和LERU ARC计划之间的主题相似性和差异.
主要成果:
- 莱鲁ARC通常集中管理任务,并负责小鼠繁殖,与美国ARC不同,研究人员管理40%左右.
- 在LERU ARC (75%) 中,冷保存是比美国 ARC (30%) 更常见的收费服务.
- LERU ARCs的非人类灵长类动物数量较少,没有狗,具有平衡的生物体住房和程序空间,并报告了更高的殖民地健康标准 (例如,没有Helicobacter和murine norovirus) 和更多的环境监测.
结论:
- 美国和LERU学术动物研究中心在运营模式,服务提供,动物普查,设施空间分配和健康监测方面存在显著差异.
- 莱鲁ARC显示了集中管理,冷保存等专业服务以及对动物群落严格的健康监测的趋势.
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