患者对生活在严重的 Prurigo Nodularis 的观点
Danielle Rodriguez1, Shawn G Kwatra2, Carla Dias-Barbosa3
1Evidera, Seattle, Washington.
JAMA dermatology
|September 20, 2023
概括
节炎 (PN) 通过和睡眠障碍显著影响患者. 了解这些患者报告的症状和对生活质量的影响对于临床试验和护理至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 定性研究是指质量研究.
- 患者报告的结果
背景情况:
- 对结节炎 (PN) 的定性研究是有限的,导致对患者优先考虑的症状和影响的理解较差.
- 患者的观点对于开发有效的治疗方法和改善PN患者的生活质量至关重要.
研究的目的:
- 为了探索患有prurigo nodularis (PN) 症状的患者经验.
- 了解PN对患者日常生活和福祉的多方面的影响.
主要方法:
- 对21名美国成年人进行了定性,一对一的电话采访,诊断出prurigo nodularis (PN).
- 参与者通过患者协会,小组和社交媒体招募.
- 用内容分析分析分析了采访成绩单,以确定关键症状和影响.
主要成果:
- 所有参与者都报告过,疼痛,出血/和皮肤干燥;经常被列为最严重的症状.
- 其他常见症状包括块/块,皮,灼伤,刺痛,病变和皮肤变色.
- 对生活质量的重大影响包括睡眠障碍,日常活动,情绪,人际关系,社交生活和工作/学校,情绪障碍是最显著的.
结论:
- ,睡眠障碍和其他报告的症状和影响是结节 (PN) 管理的关键考虑因素.
- 结果可以为PN临床试验中的终点选择提供信息.
- 结果支持临床实践中以患者为中心的决策,用于结节炎 (PN).
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